![]() ![]() (Please note that a Linux-based operating system is required for running the ModuLand programs included. The ModuLand algorithm package described in the User Guide containing several sub-methods of the ModuLand program family and also including all network data used in the manuscript.Download it! In case of any further errors or missing methods feel free to contact us at A detailed User Guide to use the original ModuLand program package containing several sub-methods of the ModuLand program family. Thanking for the advice of our colleagues we have revised this Table, and placed the revised version here. Also, the original Supplementary Table 2 missed a few modularization methods. In the PLoS ONE paper that despite of our efforts - regretfully - a few errors occurred in the original Supplementary Table 2. Electronic Supplementary Material (ESM1) of the manuscript containing a detailed description of the ModuLand method including the pseudo-codes of all algorithms used, 14 Figures, 3 Tables (with 18 module definitions, 129 different modularization methods, 13 module comparision methods), a Supplementary Discussion and 384 references.Supporting web-site with all downloadable algorithms: Featured in the February 2011 issue of Science Signaling (2010) Community landscapes: a novel, integrative approach for the determination of overlapping network modules. Kovács, I.A., Palotai, R., Szalay-Bekő, M.ModuLand method: full package containing the NodeLand, LinkLand, Perturland, Edgeweight, ProportionalHill, GradientHill and Totalhill methods Changes of version 1.3 (June 2012) The random samples can be downloaded from here and the Python scripts creating the subnetworks are available here. ![]() In the publication we also analyzed 2000 connected random subnetworks of the E.Several example networks in standard GML network format and Cytoscape Session (CYS) format can be downloaded here.compatible former version can be downloaded from here: ĭownload Cytoscape 3.0-compatible plugin and Register for newsletters! The current version is compatible with Cytoscape 3.0. The ModuLand Cytoscape plug-in containing the optimal LinkLand version of the ModuLand method.A detailed User Guide and Installation Instruction for the Cytoscape plug-in version of the optimal LinkLand version of the ModuLand method.Supplementary Material of the manuscript.(2012) ModuLand plug-in for Cytoscape: extensively overlapping network modules, community centrality and their use in biological networks. Szalay-Bekő, M., Palotai, R., Szappanos, B., Kovács, I.A., Papp, B.ModuLand: Cytoscape plug-in containing the Linkland and ProportionalHill methods As various adaptations of the method family, we developed several algorithms, which provide an efficient analysis of weighted and directed networks, and (1) determine overlapping modules with high resolution (2) uncover a detailed hierarchical network structure allowing an efficient, zoom-in analysis of large networks (3) allow the determination of key network nodes and (4) help to predict network dynamics.Ĭonclusions/Significance: The concept opens a wide range of possibilities to develop new approaches and applications including network routing, classification, comparison and prediction. Methodology/Principal Findings: Here we introduce the novel concept of ModuLand and its plug-in to the widely used Cytoscape progam, an integrative method family determining overlapping network modules as hills of an influence function-based, centrality-type community landscape, and including several widely used modularization methods as special cases. However, the development of a method, which is both fast and accurate, provides modular overlaps and partitions of a heterogeneous network, has proven to be rather difficult. Background: Network communities help the functional organization and evolution of complex networks. ![]()
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